Genomic Object Net: Petri Net Enhancement for Multi-Cellular Processes

نویسندگان

  • Yuichi Hirata
  • Hiroshi Matsuno
  • Makiko Sasaki
  • Satoru Miyano
چکیده

Recent study of cell lineage of multi-cellular organism such as C. elegans shows us that cell-cell interaction and localization of gene products take very important role in the development of early embryo [3]. In order to describe such multi-cellular processes, we extend the software tool Genomic Object Net [2, 4] in which we enhanced the hybrid parametrized functional Petri net (HPFPN) model to extend the parameter space of elements of Petri net and carry out the dynamical change of Petri net.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Simulated Cell Division Processes of the Xenopus Cell Cycle Pathway by Genomic Object Net

Matsuno et al.[1] modeled and simulated that multicellular patterning by the Drosophila Delta-Notch signaling pathway by using the software "Genomic Object Net" which was developed based on hybrid functional Petri net (HFPN) architecture. In this model, cellular formation is fixed throughout the simulation. This paper constructs an HFPN model of the Xenopus cell cycle pathway, which includes th...

متن کامل

Genomic Object Net: XML Visualization of Simulation Results from Biological Modeling on Hybrid Functional Petri Net

In [2], we showed that hybrid Petri net (HPN) provides the promising basic architecture for representing biological processes with an example of description and simulation of λ phage genetic switch mechanism. We launched the project “Genomic Object Net Project” whose aim is to develop the software tool which can be used by biologist easily and intuitively. As a first step, in [3], we introduced...

متن کامل

Xenopus Cell Cycle Pathway for Simulating Cell Division Processes by Genomic Object Net

To establish methods for modeling multicellular systems is the current important issues in biopathway simulations. This paper proposed a new method for modeling cell division processes with using a famous multicellular phenomenon “the changes in cell division cycles from synchronous to asynchronous in Xenopus” and succeeded in simulating this phenomenon with GON. Matsuno et al. [3] modeled and ...

متن کامل

Availability evaluation of Software architecture of object oriented Style using coloured Petri nets

Software architecture is one of the most fundamental products in the process of software development in the areas of behavioral or non- behavioral features like availability or transformability change. There are different ways to evaluate software architecture one of which is the creation of application model. An executable model of software architecture is an official description of architectu...

متن کامل

Modeling and Simulation of Fission Yeast Cell Cycle on Hybrid Functional Petri Net

Through many researches on modeling and analyzing biological pathways, Petri net has recognized as a promising method for representing biological pathways. Recently, Matsuno et. al. (2003) introduced hybrid functional Petri net (HFPN) for giving more intuitive and natural biological pathway modeling method than existing Petri nets. They also developed Genomic Object Net (GON) which employs the ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2001